 gel filtrat solubl protein normal cataract human lens solubl protein normal cataract lens separ molecular size polysaccharid gel sephadex g-100 cataract well normal lens 4 compo- nent evolut cataract pre- ferenti decreas low molecular weight protein len disappear complet matur hypermatur cataract hand protein high molecular weight -crystallin resist patholog process electrophoret pattern low molecular weight protein normal len revea- led fraction distribut larg mobil area immunoelectrophoresi 3 precipitin line 