 studi perfus hypothermia special refer deep hypothermia circulatori arrest 1 perfus hypothermia produc larg temperatur gradient bodi organ cool roughli proport basal blood flow differ coldest warmest portion bodi 30 minut perfus exce 25 2 averag bodi temperatur proper measur total bodi cool calcul arterioven temperatur differ extracorpor flow rate 3 true deep hypothermia obtain reason period perfus 4 rise core temperatur occur circulatori arrest hypothermia high averag bodi temperatur 5 high averag bodi temperatur lead continu product lactic acid muscl tissu low core temperatur impair lactic acid metabol metabol acidosi progress prolong perfus hypothermia accentu total circulatori arrest progress acidosi minim uniform profound cool combin extern perfus hypothermia 6 diluent appear total bodi heat exchang perfus cool 7 perfus warm differenti greater core organ brought normal rang anim remain cold 