 select protein excret patient nephrot syndrom gel diffus precipitin techniqu commerci prepar antisera urin plasma ratio specif protein determin individu protein clearanc express percentag transferrin clearanc plot ordin respect molecular weight log-log graph straight evid graphic constant estim method squar slope express determin slope express degre glomerular select protein excret sixti-five determin perform 48 patient 45 satisfi usual criteria nephrot syndrom 1 patient primari renal diseas nephrot syndrom displai high select type proteinuria greater averag group + 1 sd respond initi steroid therapi acut subacut glomerular chang observ renal biopsi 2 patient chronic renal diseas nephrot syndrom displai averag frequent low select type proteinuria 3 appear characterist type select patholog group patient nephrot syndrom 4 degre select protein excret total daili amount protein excret time remain fairli constant despit fluctuat amount protein excret 5 slight correl borderlin signific degre select protein excret durat diseas initi para-aminohippur acid clearanc 6 statist correl exist initi blood urea nitrogen inulin clearanc select type protein excret patient azotem initi near-normal inulin clearanc averag select type better 7 suggest adult patient initi azotem grossli abnorm inulin clearanc respons therapi blood urea nitrogen normal inulin clearanc normal respons therapi predict degre accuraci studi adult patient nephrot syndrom requir substanti premis 