 analysi organ knowledg retriev in univers mode call 'pure' 'basic' keep mind applic scienc prefer word 'basic' differ in good collect data haphazardli on isol defin problem control condit interf factor elimin prefer narrow problem manag proport it essenti approach problem sort hypothesi theori situat concentr obtain evid hypothesi the task devis crucial experi answer effici if answer disprov hypothesi evid construct hypothesi confirm hypothesi readi step forward research easier fulli control reproduc situat biolog human situat recours statist method alter gener methodolog on find clear methodolog lack field scienc todai 